Requiring as little as 5g of API, ASD-HIPROS rapidly screens for the best combination of drug loads, excipients – including Dispersome® BLG novel protein-based excipient – and surfactants with an advanced computational tool followed by Spray Drying of up to 24 of the most promising formulations.
This 3 step screening process is able to provide you, in just 6 weeks, with an accurate assessment of all formulation prototypes:
Detailed Assessment Reports
ASD-HIPROS narrows down formulation options, comparing them in terms of bioavailability and stability, to provide a detailed assessment report including:
Formulation space definition and evaluation;
List of 24 viable formulations tested experimentally;
Processed analytical results for up to 24 formulation prototypes;
Formulation ranking, comparing bioavailability and stability, identifying the best formulations;
Options on how to proceed with your drug candidate
ASD-HIPROS enables a seamless experience for you and your drug candidate. A fast and efficient screening platform able to identify the best performing and stable formulations for your drug. In just 6 weeks, this platform maximizes your chances of identifying a successful formulation, accelerating the development towards commercial manufacturing and patient availability.
ASD-HIPROS includes distinct features such as:
Requires minimal API – as little as 5g of your API for the full service;
Rational formulation definition using in silico computational modeling;
Access to innovative proprietary excipients such as Dispersome® – BLG
Testing of a high number of Spray Drying prototypes (up to 24) to screen for most promising formulations;
Rapid turnaround time in as little as 6 weeks;
Flexible operation space, maximizing formulation combinations with different drug loads, polymers and surfactants;
Single point of contact for improved communication.
Why rely on us?
Hovione is a CDMO with more than 15 years of accumulated experience and expertize in Spray Drying development and manufacture. Hovione offers a clear path to clinical supplies and commercialization by combining modeling capabilities and extensive process knowledge with manufacturing capacity and an excellent approval track record.
- Screening Methodologies for the Development of Spray-Dried Amorphous Solid Dispersions
- Amorphous solid dispersions - Increasing Solubility From API to Tablets
Watch On-Demand Webinar
Amorphous Solid Dispersions by Spray Drying from Bench to Market/press-room/events/webinar-amorphous-solid-dispersions-spray-drying-bench-market