Drug Substance Development
Hovione designs smarter, safer, and more efficient API processes—built on science, strengthened by data, enriched by experience, and ready for scale—helping you move faster, control complexity, and bring your product to market with confidence.
Turning complex chemistry into scalable success
At Hovione, we make your molecule journey smoother, faster, and predictable. Our Process Chemistry Development team combines deep scientific expertise with advanced tools to design scalable, reliable, and high-quality API processes that deliver results from early development through commercial manufacturing.
We take a data-driven, model-informed approach from day one, using data-rich experimentation, modelling, and Quality by Design to quickly understand your process and eliminate challenges during scale-up. This means faster decisions and a more efficient path for your project from early-stage development, ensuring reliable scale-up and faster market entry.
Uncompromising safety
Rigorous process safety studies underpin all our work, enabling safe execution of complex chemistries such as cryogenic, organometallic reactions, and hydrogenation. This disciplined approach allows us to engineer processes that remain safe, reliable, and effective at every scale and stage.
Engineering solid‑state performance
Our solid state and particle engineering expertise is a major differentiator. We design robust crystallization processes that deliver the right purity, particle size, and morphology while improving filtration and drying performance. When needed, spherical agglomeration technology enhances flowability, compressibility, and enables direct compression—streamlining your downstream steps.
To keep development on track, we use advanced Process Analytical Technologies (PAT) tools such as Raman, Fourier transform infrared spectroscopy (FTIR), near-infrared spectroscopy (NIR), and real-time crystallization monitors. These tools provide immediate insight into reactions and critical steps, helping us optimize faster and ensure process robustness before reaching GMP scale.
Sustainability by design
We are committed to sustainability by design and efficient chemistry, applying greener solvents, flow chemistry, and chemistry in water options — reducing cost, waste, and environmental impact.
Contact us to learn how we are turning complex chemistry into scalable success.
Britest at the heart of EDaM
Download our approach document.
http://go.hovione.com/l/47122/2014-09-10/l5f9?open=http://go.hovione.com/l/47122/2014-08-05/97gh/47122/11108/britest_poster.pdf