Press Room

AAPS 2017

Start
Sunday, November 12, 2017 - 00:00
End
Wednesday, November 15, 2017 - 00:00
Location: San Diego, United States
Booth Number: 2806
Spray Drying Contract Manufacturing large capacity | Hovione

Hovione will be attending AAPS 2017 in San Diego, United States.

Schedule meeting - AAPS 2017| Hovione

HOVIONE POSTERS

Benchmarking melt processing techniques for taste masking applications

Slavomira Doktorovova, Inês Matos, Peter Stayer, Márcio Temtem, João Henriques

Bio-relevant vs traditional dissolution methodologies: a comparison study between USP II and USP IV apparatuses

Mafalda Paiva, Luís Sousa, Pedro Serôdio, Constança Cacela

Optimizing Disintegration in Tablets of Amorphous Solid Dispersions

Nuno Neves, João Henriques, Márcio Temtem

Enhancing Amorphous Solid Dispersion Miscibility and Drug Saturation through Ternary Systems

Traciann Scirbona, Michael Puppolo, Iris Duarte, João Henriques, Rui Ferreira, David Storey, Dirce Macário

Compression mechanism of HPMC-AS based amorphous solid dispersions

Slavomira Doktorovova, Clara Sá Couto, Márcio Temtem, João Henriques, Pedro Valente

Improving Efficiency of Taste Making through Spray Congealing

Inês Matos, Peter Stayer, João Henriques, Márcio Temtem

In vitro - in vivo correlations of carbamazepine nano-dispersions for application in formulation development

Michael Puppolo, Zachary WarnkenIris Duarte, Traciann Dillon, David Storey

Paddle Over Disk as a Dissolution Test for Orally Inhaled Fluticasone Propionate

Beatriz Noriega, Mafalda Paiva, Luisa Corvo, Eunice Costa, Filipa Maia

Spray Dried Composite Particles: Formulation and Process Parameters, Effect of two API Concentrations and Stability Assessment

Maria Palha, Raquel Barros, Cláudia Moura, Sofia Silva, Sara Cardoso, Eunice Costa, Márcio Temtem

Use of Supercritical-CO2 Assisted Spray Drying for the production of Pharmaceutical compounds

Cláudia Moura, Márcio Temtem, Eunice Costa

 

 

If you would like to discuss with us your projects and to find how Hovione can help, schedule a meeting with us. Adam Neunuebel will be pleased to meet you.

adam-neunuebel-photo

Adam Neunuebel

Head of Business Development

 

 

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In an interview with Executiva, a portuguese media outlet focused on women´s leadership, Diane Villax, co-founder and long-standing leader of Hovione, reflects on her journey and the company’s development over more than six decades. Diane Villax’s career began at a time when few women worked outside the home. At 19, she joined a trading company as a foreign languages correspondent, where she developed essential business skills — including commercial correspondence, banking and export procedures — that later proved instrumental in helping her husband, Ivan Villax, establish Hovione in 1959. From its earliest days operating in the family home in Lisbon, Hovione adopted an international outlook. The company’s first major customers were in Japan, setting demanding quality standards that helped shape its long-term position in global markets. Over the following decades, Hovione expanded its footprint with the construction of its first manufacturing site in Loures (1969), followed by expansion to Macau (1986), the United States (New Jersey, early 2000s) and Ireland (Cork). The company grew into a global organization with more than 2,500 employees — including over 300 scientists — and a reputation as a preferred supplier to leading pharmaceutical companies worldwide. Throughout the interview, Diane highlights the values that have guided the company’s development: a commitment to excellence, a strong work ethic, and a focus on quality and long-term relationships. Although she did not have formal business training, she learned “on the job” and brought discipline, precision and structure to her role — particularly in the company’s early financial and administrative leadership. Now in her nineties and an active member of Hovione’s Board of Directors, Diane Villax remains engaged with the company’s evolution and governance, reflecting a continued commitment to its long-term development. Her story reflects entrepreneurial drive, resilience and long-term leadership — and offers insight into the values that have shaped Hovione’s trajectory for more than six decades. Read the full interview at Executiva.pt (in portuguese).    

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Márcio Temtem, vice president, Strategic Business Management, Hovione, addresses molecule complexity, speed, and regionalization via integrated manufacturing. The landscape of small molecule manufacturing is rapidly evolving, according to Márcio Temtem, vice president, Strategic Business Development, Hovione, who provides an expert look into how his firm is evolving their approach as the industry changes. With 17 years of experience at Hovione, a family-owned CDMO with a 66-year legacy, Temtem identifies three pivotal trends currently shaping the industry: increased complexity, accelerated development speed, and the regionalization of supply chains. Temtem observes that small molecules have grown significantly in size and complexity, often requiring multiple chemical steps and high-potency handling. This shift necessitates a specialized "toolbox" to overcome modern bioavailability challenges. Highlighting Hovione's technical approach to these hurdles, Temtem states, "We use a platform called amorphous solid dispersions, produced by spray drying to address this challenge of bioavailability.” This platform represents a core area in which Hovione maintains global leadership, utilizing innovative tools to scale processes efficiently while minimizing the use of APIs. Temtem also mentions the increased influence of AI in drug discovery and deployment, which requires CDMOs to bridge the gap from grams to tons at a much faster pace than in previous years. He further addresses the trend of regionalization, noting the rise of countries such as the US and China prioritizing regional supply chain strategies. He explains that Hovione is uniquely positioned to navigate these new challenges with supply chains through its FDA-inspected sites across three continents. Central to Hovione’s competitive advantage is their integrated manufacturing offer, which combines drug substance and drug product expertise at a single location. Temtem emphasizes the value of this model, stating, “The company… has been investing in an integrated offer, bridging the problems of chemists and formulators all at the same shop.” To support this integration, the company continues to pioneer advanced manufacturing avenues, including continuous flow for drug substances and continuous tableting for drug products. Watch the full video interview or read the transcript at PharmTech.com  

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Hovione’s Strategy for Complexity, Speed, and Regional Supply Chains

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