Knowledge Center

Patent / Jan 01, 1976

16.beta.-Methyl-17-hydroxypregna-1,4,9(11)-triene-3,20-dione

Authors:
Source:
GB 1397267

The title compd. I was prepd. from pregnanetrione II. Thus, ketalization of II using HOCH2CH2OH followed by redn. using KBH4 and then dehydration gave pregnene III. The Grignard reaction of III and MeMgBr followed by acid hydrolysis and bromination-dehydrobromination gave I.

Also in the Knowledge Center

Related Content

Hovione and GEA set new standards for continuous tableting

Press Release / Dec 02, 2025
Article
View

Drug Substance Manufacturing

We have an exceptional range of flexible manufacturing equipment to ensure availability and suitability for our customers’ manufacturing needs.

Page
Read more