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Press Clipping / Jan 24, 2022

Hovione will expand 3 pharmaceutical chemistry facilities

C&EN, 21 November 2021

The Portuguese drug services firm Hovione has outlined a $170 million investment program through 2023 that it says will increase its production capacity by about 25%. In East Windsor, New Jersey, where Hovione is investing $50 million, the company will add two spray dryers, tripling capacity, and expand its capacity to make research- and small-scale quantities of active pharmaceutical ingredients (APIs). “We are looking to build this up to a significant site for Hovione with more than 300 people,” says Jean-Luc Herbeaux, the firm’s chief operating officer.

Hovione currently employs about 150 people in New Jersey. In Cork, Ireland, it will spend about $50 million to upgrade its high-potency API production and add a spray dryer.

In Loures, Portugal, Hovione is spending $70 million on additions such as a new manufacturing building and an eight-lab quality control facility. These projects, some of which are already complete, will take up all the available space at the Loures site, according to CEO Guy Villax. “Last year we broke $300 million in sales,” Villax says, and the firm is targeting $400 million this year. “The company needs to be less Portuguese. You will see us invest and grow our footprint more in the US than elsewhere.”The Portuguese drug services firm Hovione has outlined a $170 million investment program through 2023 that it says will increase its production capacity by about 25%.

In East Windsor, New Jersey, where Hovione is investing $50 million, the company will add two spray dryers, tripling capacity, and expand its capacity to make research- and small-scale quantities of active pharmaceutical ingredients (APIs). “We are looking to build this up to a significant site for Hovione with more than 300 people,” says Jean-Luc Herbeaux, the firm’s chief operating officer. Hovione currently employs about 150 people in New Jersey.

In Cork, Ireland, it will spend about $50 million to upgrade its high-potency API production and add a spray dryer.

In Loures, Portugal, Hovione is spending $70 million on additions such as a new manufacturing building and an eight-lab quality control facility. These projects, some of which are already complete, will take up all the available space at the Loures site, according to CEO Guy Villax. “Last year we broke $300 million in sales,” Villax says, and the firm is targeting $400 million this year. “The company needs to be less Portuguese. You will see us invest and grow our footprint more in the US than elsewhere.”

 

Read the entire article on CEN.acs.org

 

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Hovione is bringing momentum to the intranasal field after announcing that its lead single-use nasal dry powder device, developed in collaboration with Industrial Design Consultancy Ltd (IDC), is now available for commercial partnerships. The milestone marks the transition from prototype to a fully integrated intranasal drug delivery platform that spans Hovione’s end-to-end partnership capabilities–from API synthesis through advanced formulation and particle engineering to drug product manufacturing, including device supply and advanced analytical tools for nasal performance characterization. The platform’s single-use device is designed to be manufacturable at scale and to leverage existing advanced particle engineering and drug product manufacturing capabilities, a practical advantage that can shorten timelines to clinic and commercialization while reducing development risk and cost. The device’s patented mechanism supports targeted nasal deposition, including access to the upper olfactory region. This enables rapid systemic absorption and potential nose-to-brain delivery pathways that are increasingly important for CNS and emergency-use indications. Beyond the single-use format, Hovione and IDC are advancing a multi-dose variant to broaden applicability across dosing regimens and therapeutic areas. The collaboration is backed by an intellectual property portfolio and initial patent grants, positioning the platform as a turnkey option for pharma partners seeking a single integrated supplier for both drug substance and device. This development arrives as intranasal delivery gains traction for systemic, CNS and rapid-onset therapies. This is precisely the focus of the upcoming 4th Nasal Formulation & Delivery Summit, for which Hovione is a key sponsor. The annual summit unites formulation, delivery and product development leaders to tackle drug-device compatibility, translational preclinical models, and strategies for scalable, regulatory-ready intranasal programs. Hovione’s recent progress will be highly relevant to attendees looking to de-risk nose-to-brain and systemic intranasal programs. Read the full article at News-Medical.net    

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