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Press Clipping / Mar 06, 2022

Hovione promotes Herbeaux to CEO

C&EN, 6 March 2022

Hovione has appointed as CEO its chief operating officer, Jean-Luc Herbeaux, effective April 1. Herbeaux succeeds Guy Villax, who has been CEO of the family-owned pharmaceutical services company for 25 years. Herbeaux joined the firm in 2020. He previously held several management positions at the German chemical maker Evonik Industries, where his final role was head of the health-care business. In November, he and Villax outlined a $170 million investment program through 2023 that they said will increase Hovione’s production capacity by about 25%. Villax is credited with moving the company into the exclusive synthesis of active pharmaceutical ingredients (APIs) for drug industry customers. Hovione, one of several family-owned drug services companies in Europe, saw sales grow by 10 times under Villax’s stewardship. Major investments included the purchase of a Pfizer plant in Ireland in 2009. Villax says Hovione’s board chose to hire a nonfamily CEO in response to growth over the past 5 years. “When a company employs 1,600 or 1,700, you need skills that other people have much more developed than I have,” he tells C&EN. Hovione has about 2,000 employees.

 

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Hovione is bringing momentum to the intranasal field after announcing that its lead single-use nasal dry powder device, developed in collaboration with Industrial Design Consultancy Ltd (IDC), is now available for commercial partnerships. The milestone marks the transition from prototype to a fully integrated intranasal drug delivery platform that spans Hovione’s end-to-end partnership capabilities–from API synthesis through advanced formulation and particle engineering to drug product manufacturing, including device supply and advanced analytical tools for nasal performance characterization. The platform’s single-use device is designed to be manufacturable at scale and to leverage existing advanced particle engineering and drug product manufacturing capabilities, a practical advantage that can shorten timelines to clinic and commercialization while reducing development risk and cost. The device’s patented mechanism supports targeted nasal deposition, including access to the upper olfactory region. This enables rapid systemic absorption and potential nose-to-brain delivery pathways that are increasingly important for CNS and emergency-use indications. Beyond the single-use format, Hovione and IDC are advancing a multi-dose variant to broaden applicability across dosing regimens and therapeutic areas. The collaboration is backed by an intellectual property portfolio and initial patent grants, positioning the platform as a turnkey option for pharma partners seeking a single integrated supplier for both drug substance and device. This development arrives as intranasal delivery gains traction for systemic, CNS and rapid-onset therapies. This is precisely the focus of the upcoming 4th Nasal Formulation & Delivery Summit, for which Hovione is a key sponsor. The annual summit unites formulation, delivery and product development leaders to tackle drug-device compatibility, translational preclinical models, and strategies for scalable, regulatory-ready intranasal programs. Hovione’s recent progress will be highly relevant to attendees looking to de-risk nose-to-brain and systemic intranasal programs. Read the full article at News-Medical.net    

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