Press Room

News / Jun 23, 2023

2023 International Women Engineering Day

Make Safe Seen

International Women in Engineering Day_Hovione

This year’s theme for International Women in Engineering Day is #makesafetyseen to celebrate the achievements of women around the world in engineering.

Hear from some of our engineers as they share their career journeys and empower others to break barriers in the healthcare field.

Thank you to Ana Rafael (Principal HSE Specialist) Catarina Coelho (Senior QC Technical Specialist), and Luísa Paulo (Corporate Quality Senior Director I) for making safety seen.

 Read their statements here.

2023 International Women Engineering Day_Ana Rafael | Hovione

“I would like to say a word to empower young girls and show them the incredible potential of women in engineering. Engineering is not just about math and science — it's about designing safer, environmentally friendly systems, collaborating, and embracing entrepreneurship. As women in engineering, we are making a profound impact on society.

I proudly graduated in Chemical Engineering from the University of Coimbra, where both boys and girls were determined to leave their mark on the world. I began my career as a researcher, simulating distillation processes. However, my passion for the environment led me to shift my focus towards engineering design for biofuels and environmental treatment plants. It was then that everything fell into place — I knew I wanted to create a better world.

Years later, I seized the opportunity to start my own business, dedicated to enhancing the environmental efficiency and sustainability of various industries across Europe, KSA, and Angola. This journey taught me the importance of sustainable practices and the dedication required to secure our place in the future.

Today, at Hovione, I’m able to balance both of my passions: contributing to life-saving medicines and ensuring that all of us do our jobs in a safely manner. For ourselves and for the communities where we are in. For the past 8 years, I have led and managed teams and projects, guiding Hovione sites towards a better, safer and more sustainable future. I never stop learning and embracing challenges.

I believe in the power of women, driving positive change and breaking barriers. Together, we can create a safer world where women in engineering thrive and shape a brighter future for all."

Ana Rafael - Principal HSE Specialist
Hovione Portugal 

2023 International Women Engineering Day_Catarina Coelho | Hovione

"On International Women in Engineering Day, I take this time to reflect on my journey as a woman in the engineering field.

One of the most rewarding experiences in my journey was the opportunity to work as Senior Analytical Chemist at Hovione. In this role, I had the privilege of contributing to the design and implementation of innovative solutions.

On this special day, let us celebrate the remarkable achievements of women engineers worldwide. Together, we are transforming the landscape of engineering, breaking down barriers and forging a path for future generations of aspiring engineers."

Catarina Coelho - Senior QC Technical Specialist
Hovione Portugal

2023 International Women Engineering Day_ Luísa Paulo | Hovione

"I have been working as a Chemical Engineer for 40 years and I would like to motivate the young women who love engineering to pursue their dream. At Hovione, I have always felt appreciated and encouraged by my colleagues."

Luísa Paulo - Corporate Quality Senior Director I
Hovione New Jersey

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Continuous Tableting (CT) is defined as continuous manufacturing of oral dose drugs, specifically tablets. As per ICH's Q13 definition1, a continuous manufacturing process in the pharmaceutical industry comprises at least two unit operations integrated from a mechanical and software perspective. There is a wide combination of possible CT process configurations that are dependent on the needs of the intended product formulation and each of the individual unit operations that constitute the process train can be continuous, semi-continuous, or batch processes. The typical manufacturing processes for tablet formulation are direct compression (DC), dry granulation (DG) and wet granulation (WG)2 - details on these manufacturing processes are beyond the scope of this article, so the interested reader is directed to relevant literature. The actual implementation of CT technology in a facility can broadly vary depending on the level of desired integration and automation. Process trains can be designed to be flexible and converted between multiple configurations (e.g. continuous DC, DG and WG), controlled by the end user from one single software and within a single clean room. The other possibility would be for subsections of the CT process to be divided into multiple clean rooms where inprocess materials are transferred between suites via a bin-to-bin approach (e.g. a granulation suite to prepare granules from raw materials followed by continuous DC (CDC) to blend the granules and produce tablets). The level of automation and instrumentation designed into the CT process (typically involving Process Analytical Technologies, PAT) can open the possibility to implement sophisticated control strategies. Key components of a control strategy that need to be considered for CT are material tracking and genealogy, knowledge of the residence time distribution (RTD), and in-process controls (spectroscopic and/or soft sensors based on process parameters). Holistically, these control strategy elements enable the implementation of a material diversion strategy to automatically divert out of specification material from the process. In their most advanced form, control strategies may also enable real time release testing (RTRt) of the final tablet drug product and reduce the off-line analytical burden and the number of operators needed to manage the process.   Read the full article at  


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