Press Room

Rx-360 Annual Conference - Partnering for Patients

Start
Thursday, November 03, 2016 - 08:30
End
Friday, November 04, 2016 - 16:00
Location: Washington DC, United States

Why Attend?
Inspiration. Collaboration. Commitment.

The quality revolution is here. What are you doing about it?
Rx-360 connects and build relationships to foster quality patient care – a goal of every healthcare system. New disease outbreaks, new regulations, new medicinal demands and new consumer expectations are driving the shift to ensure the security of supply chains from upstream suppliers of components to finished product manufacturers all the way to the patient. Hear from industry leaders how they are tackling the challenges they experience in delivering primary interventions to treat patients. Participate in a hands-on learning experience on what’s new and thriving in the world of quality and supply chain security for healthcare.

You will be empowered to meet global challenges through best practices and through organizations like Rx-360, a powerful competitive advantage.

Rx-360 brings together thought leaders, industry pioneers, and your peers for two days of idea sharing. Join Hovione and other Rx-360's members.

Who should attend?

  • Pharmaceuticals
  • Medical Devices
  • Biotech
  • Suppliers
  • Government
  • Academicians
  • Pharmacists
  • Practitioners
  • Students

Also, Guy Villax will be speaker at the Conference as Chairman of the Rx-360 Consortium.

Learn more about other speakers and agenda details.

Don’t forget to register for Rx-360 Annual Conference ‘16 and get ready for a transformational experience.

Also in the Press Room

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Continuous Tableting (CT) is defined as continuous manufacturing of oral dose drugs, specifically tablets. As per ICH's Q13 definition1, a continuous manufacturing process in the pharmaceutical industry comprises at least two unit operations integrated from a mechanical and software perspective. There is a wide combination of possible CT process configurations that are dependent on the needs of the intended product formulation and each of the individual unit operations that constitute the process train can be continuous, semi-continuous, or batch processes. The typical manufacturing processes for tablet formulation are direct compression (DC), dry granulation (DG) and wet granulation (WG)2 - details on these manufacturing processes are beyond the scope of this article, so the interested reader is directed to relevant literature. The actual implementation of CT technology in a facility can broadly vary depending on the level of desired integration and automation. Process trains can be designed to be flexible and converted between multiple configurations (e.g. continuous DC, DG and WG), controlled by the end user from one single software and within a single clean room. The other possibility would be for subsections of the CT process to be divided into multiple clean rooms where inprocess materials are transferred between suites via a bin-to-bin approach (e.g. a granulation suite to prepare granules from raw materials followed by continuous DC (CDC) to blend the granules and produce tablets). The level of automation and instrumentation designed into the CT process (typically involving Process Analytical Technologies, PAT) can open the possibility to implement sophisticated control strategies. Key components of a control strategy that need to be considered for CT are material tracking and genealogy, knowledge of the residence time distribution (RTD), and in-process controls (spectroscopic and/or soft sensors based on process parameters). Holistically, these control strategy elements enable the implementation of a material diversion strategy to automatically divert out of specification material from the process. In their most advanced form, control strategies may also enable real time release testing (RTRt) of the final tablet drug product and reduce the off-line analytical burden and the number of operators needed to manage the process.   Read the full article at gmp-journal.com  

Article

Continuous Tableting and the Road to Global Adoption

Mar 04, 2024