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Patent / Jan 01, 1972

Polymetaphosphate complexes of .alpha.-6-deoxy-5-hydroxy tetracyclines

Authors:

Ivan Villax

Source:

DE 2152476

The title Na phosphate complexes, useful as antibiotics and more sol. in water than the corresponding acid complexes, were prepd. by reaction of the tetracycline with Na hexametaphosphate or HPO3 then NaOH in an inert org. solvent, e.g., DMF, EtOH, MeOH, or CHCl3.

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Knowledge Center

Polymetaphosphate complexes of .alpha.-6-deoxy-5-hydroxy tetracyclines

Also in the Knowledge Center

Methodology for rapid development of a continuous loss-in-weight feeding process

A review of the state-of-the-art: progress in ultrasonic and acoustic techniques for quality assessment in the development and manufacturing of oral solid dosage forms - Part I: theoretical foundations and principles

An integrated analytical approach to evaluate powder aggregation and predict the aerodynamic performance of homogeneous powders

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