Knowledge Center

Patent / Jan 01, 1976

16.beta.-Methyl-17-hydroxypregna-1,4,9(11)-triene-3,20-dione

Authors:
Source:
GB 1397267

The title compd. I was prepd. from pregnanetrione II. Thus, ketalization of II using HOCH2CH2OH followed by redn. using KBH4 and then dehydration gave pregnene III. The Grignard reaction of III and MeMgBr followed by acid hydrolysis and bromination-dehydrobromination gave I.

Also in the Knowledge Center

Related Content

Membrane Technology

Hovione has a wide range of membrane capabilities at its disposal including nanofiltration and ultrafiltration.

Page
Read more

Inhalation grade particles

Hovione is a global expert in particle engineering, an essential technology when developing inhalation drug products.

Page
Read more

Hovione’s contributions to the Sustainable Development Goals

Hovione has aligned its Sustainability Policy and Strategy to the United Nations Sustainable Development Goals

Page
Read more