Press Room

Webinar - Analytical Sciences of Amorphous Solid Dispersions

Start
Thursday, October 01, 2020 - 16:00
End
Thursday, October 01, 2020 - 16:00
Location: online

Thursday, October 1st, 2020  |  8 AM (PDT), 11 AM (EDT), 4 PM (GMT)

 

Watch On-Demand Webinar

 

 

Speakers

João Pereira - Team Leader, R&D Analytical Development
Susana Campos - Group Leader, R&D Analytical Development

 

Amorphous solid dispersions (ASDs) are a promising formulation approach to overcome solubility challenges of poorly water-soluble drugs. However, close monitoring of physical transformations is required to ensure both product’s processability and shelf-life. Detection of low-level physical transformations is important not only to evaluate and forecast product’s stability but also to correlate with product performance.

This webinar will present Hovione’s approach for the characterization of amorphous solid dispersions (ASD) throughout manufacturing process and product shelf-life. In detail, the use of orthogonal solid state and particle characterization techniques, such as XRD, DSC, IR, Raman and SEM, will be presented in a few case studies.

In this webinar you’ll learn:

  • How to understand and characterize ASD physical stability

  • What are the most suitable techniques for ASD characterization

  • Linking processability and physical transformations of ASD

Watch On-Demand Webinar

 

 

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Integrated approach simplifies development, reduces risk, and supports scalable manufacturing. Hovione and Industrial Design Consultancy Ltd.’s (IDC) lead single-use nasal dry powder device is now available for commercial partnerships. Hovione and IDC have completed the device design and established initial device manufacturing and supply capability, enabling pharmaceutical partners to leverage existing capsule filling infrastructure. This approach simplifies development, reduces cost and risk, and helps shorten timelines to the clinic and commercialization. “This milestone marks an important step in the evolution of our collaboration with IDC — from device innovation to a fully integrated intranasal drug delivery platform,” said Márcio Temtem, Ph.D., Vice President, Strategic Business Management, Hovione. “As the industry looks for faster, more reliable ways to bring complex therapies to patients, integration becomes critical. By bringing together nasal particle engineering science, formulation manufacturing and filling, and device technologies into a single offering, we enable a more seamless and predictable development journey, accelerating the path to market for intranasal therapies.” The nasal delivery device enables broad and targeted nasal deposition flexibility while delivering maximum usability and reliability. With a patented design and manufacturing process established, the platform is available for partnering with pharmaceutical companies on an exclusive basis as part of Hovione’s integrated offering for inhalation and nasal drug development and manufacturing. Additionally, IDC’s Managing Director, Stephen Knowles Ph.D., said the companies are now “well-advanced” with the development of a multi-use device to support an even wider range of therapies and patient needs. Read the full article at ContractPharma.com    

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