Press Room

RDD Europe 2015

Start
Tuesday, May 05, 2015 - 00:00
End
Friday, May 08, 2015 - 00:00
Location: Nice, France
Booth Number: Table nr. 32

RDD Europe 2015 will be held from Tuesday 5th May until Friday 8th May 2015 at the Palais des Congres d'Antibes, Nice, France. Hovione will be present with a table (nr. 32), a presentation, a workshop and a set of posters.

Contact us if you would like to schedule a meeting or to find more about the Hovione posters at RDD.

contact us button | Hovione

 

HOVIONE'S PRESENTATION

Optimized Composite Particles for API-independent Formulations with Enhanced Performance


Speaker: Eunice Costa, PhD (Scientist, Drug Product Development)

Date: Friday, May 5, 2015

Time: 8:30 AM

HOVIONE'S WORKSHOP

Trends in Inhalation Drug Development: Particle Engineering and Formulation Strategies


Speakers: Eunice Costa, PhD (Scientist, Drug Product Development)

                  Filipe Neves, PhD (Senior Scientist, Group Leader, Drug Product Development)

Date: Wednesday, May 6, 2015 

Time: tbd - afternoon from 2:00 to 6:00 PM

  • Introduction: This workshop addresses trends in particle engineering (PE) technologies, and formulation strategies to overcome problems during the development of inhalation drugs. Participants will gain insight into innovative approaches via comprehensive and diverse case studies chosen to illustrate the complexity of manufacturing processes. 

     
  • Workshop Content: Participants will learn the fundamentals of inhalation delivery, together with an overview of market trends and basic concepts associated with metered dose inhalation (MDI) and dry powder inhalation (DPI); for the latter platform, carrier based and composite particles based approaches will be emphasized. The impact of different particle engineering technologies on the final performance of both MDI and DPI (carrier based) products will be discussed. Case studies will link API properties (measured by cutting edge techniques) and formulation strategy, with the overall success of a given delivery platform. Lastly, DPI formulation based on spray dried composite particle approaches will be explored using case studies covering formulation development and process scale-up.

     
  • Outcome for Participants: The participants will gain insight into several innovative approaches, including a number of comprehensive and diverse case studies, which will illustrate the complex relationships linking inhaler design to particle engineering and formulation strategies.

     

POSTERS

Impact of the Size-Reduction Technology on the Performance of Suspension Pressurized Metered Dosed Inhalers: Benchmarking with Dry Powder Inhalers

Eunice Costa

Performance Optimization in Early DPI Development: Enabling High Dosage Drug Delivery to the Lungs Through Orifice-Based Aerosolization

João Fernandes

Benchmarking Gravimetric FSI vs ACI: Can We Expedite Aerodynamic Performance Evaluation for Composite Powders?

Isabel Lopes

Aerodynamic Performance of DPIs: Predicting the Impact of Carrier-Based Formulation Parameters

Filipa Maia

API Influence & Stability Assessment of Spray Dried Composite Particles

Cláudia Moura

Optimizing Trade-Offs Between Product Performance and Process Efficiency via Powder Rheology

Maria Palha

 

 

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Integrated approach simplifies development, reduces risk, and supports scalable manufacturing. Hovione and Industrial Design Consultancy Ltd.’s (IDC) lead single-use nasal dry powder device is now available for commercial partnerships. Hovione and IDC have completed the device design and established initial device manufacturing and supply capability, enabling pharmaceutical partners to leverage existing capsule filling infrastructure. This approach simplifies development, reduces cost and risk, and helps shorten timelines to the clinic and commercialization. “This milestone marks an important step in the evolution of our collaboration with IDC — from device innovation to a fully integrated intranasal drug delivery platform,” said Márcio Temtem, Ph.D., Vice President, Strategic Business Management, Hovione. “As the industry looks for faster, more reliable ways to bring complex therapies to patients, integration becomes critical. By bringing together nasal particle engineering science, formulation manufacturing and filling, and device technologies into a single offering, we enable a more seamless and predictable development journey, accelerating the path to market for intranasal therapies.” The nasal delivery device enables broad and targeted nasal deposition flexibility while delivering maximum usability and reliability. With a patented design and manufacturing process established, the platform is available for partnering with pharmaceutical companies on an exclusive basis as part of Hovione’s integrated offering for inhalation and nasal drug development and manufacturing. Additionally, IDC’s Managing Director, Stephen Knowles Ph.D., said the companies are now “well-advanced” with the development of a multi-use device to support an even wider range of therapies and patient needs. Read the full article at ContractPharma.com    

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