Knowledge Center
Presentation / Oct 17, 2021
Understanding Dry Powder Inhalers Formulations: Role of Surface Polarity of lactose mixtures
Hovione presentation at AAPS 2021 PharmSci 360
Source:
AAPS 2021
Track: Formulation and Delivery – Chemical
Rapid Fire: Role of Excipients in Formulation & Drug Product Development (CE)
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Presenting Author: Ricardo Gonçalves - Analytical Scientist, R&D Analytical Development
Why do we use small lactose particles to improve Dry Powder Inhaler formulations? Why sieved and milled lactose particles present different properties? This presentation explores the role of surface energetics, measured using inverse gas chromatography, in the behavior of DPI formulations and the implication on their aerodynamic performance.