Knowledge Center

Patent / Jan 01, 1984

Rhodium-containing catalysts and their application

Authors:
  • Philip Page
Source:
EP 86046

A catalyst for hydrogenating tetracycline intermediates was prepd. by treating a Rh phosphine complex with a hydrazine. Thus (Ph3P)3RhCl was treated with N2H4 to give a catalyst contg. 16.95% Rh which was used together with PPh3 to hydrogenate I (RR1 = CH2) to give I (R = Me, R1 = H) free from epimer.

Also in the Knowledge Center

Related Content

Our Policies

Our Policies (Quality, HSEE, Human Resources, Innovation & Entrepreneurship) communicate and document our values.

Page
Read more

Hot melt extrusion

Hot melt extrusion is a fast growing technology platform thas is utilized to solve difficult formulation challenges, primarily in the area of solubilization.

Page
Read more

What we do

Hovione is a Contract Development and Manufacturing Company dedicated to helping Pharmaceutical Customers bring new and off-patent drugs to market.

Page
Read more