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Patent / Jul 30, 2020

Processo para a preparação de brometo de umeclidínio

Authors:
  • Rafael Antunes
  • Luís Sousa
  • Nuno Lourenco
  • Maria Santos
  • Margarida Espadinha
Source:
PT109740B

A PRESENTE INVENÇÃO REFERE-SE A NOVOS PROCESSOS DE PREPARAÇÃO DE BROMETO DE UMECLIDÍNIO, CUJO NOME QUÍMICO É BROMETO DE 4- [HIDROXI(DIFENIL)METIL]-1-{[2-(FENILMETIL)OXI]ETIL}-1- AZONIABICICLO[2.2.2]OCTANO. QUE PERMITE OBTER UMA ÚNICA, PURA FORMA CRISTALINA COM UM NÍVEL CONSISTENTE DE CRISTALINIDADE E PUREZA QUÍMICA. O BROMETO DE UMECLIDÍNIO OBTIDO PODE SER FORMULADO EM COMPOSIÇÕES FARMACÊUTICAS CONTENDO O MESMO.

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