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Patent / Jan 01, 2011

Process for the preparation of amorphous minocycline

  • William Heggie
  • Zita Mendes
  • Rafael Antunes
PT 105199

A process was disclosed for the prepn. of the therapeutically useful anthracycline antibiotic minocycline (I) in amorphous and cryst. forms that are free of impurities, such as 4-epi-minocycline.