Knowledge Center

Patent / Jan 01, 1972

Polymetaphosphate complexes of .alpha.-6-deoxy-5-hydroxy tetracyclines

Authors:
  • Ivan Villax
Source:
DE 2152476

The title Na phosphate complexes, useful as antibiotics and more sol. in water than the corresponding acid complexes, were prepd. by reaction of the tetracycline with Na hexametaphosphate or HPO3 then NaOH in an inert org. solvent, e.g., DMF, EtOH, MeOH, or CHCl3.

Also in the Knowledge Center

Related Content

Development

Hovione offers a full range of development services in particle engineering to provides optimal solutions for your drug product.

Page
Read more

Explore what we do

Hovione is a Contract Development and Manufacturing Company dedicated to helping Pharmaceutical Customers bring new and off-patent drugs to market.

Page
Read more

Chromatography

Hovione has expanded its purification technologies to include chromatography to support development from lab to commercial scale.

Page
Read more