Knowledge Center
Patent / Jan 01, 1976
16.beta.-Methyl-17-hydroxypregna-1,4,9(11)-triene-3,20-dione
Source:
GB 1397267
The title compd. I was prepd. from pregnanetrione II. Thus, ketalization of II using HOCH2CH2OH followed by redn. using KBH4 and then dehydration gave pregnene III. The Grignard reaction of III and MeMgBr followed by acid hydrolysis and bromination-dehydrobromination gave I.
Also in the Knowledge Center
/ Nov 20, 2020
Leveraging Hollow Fibre Membranes and High Boiling Point Organic Solvents in the Production of Enteric Amorphous Solid Dispersions
Read more
Scientific Article
Scientific Article
/ Nov 18, 2020
Coupling Reaction Kinetics, Calorimetry and Mixing Studies for Successful Scale-up of Exothermic Reactions
Read more
Scientific Article