Press Room

News / Nov 25, 2021

Watch Luís Portela on Procurement Leaders' Extraordinary Stories

Procurement Leaders invited our Procurement Director to explain how Hovione produced and offered sanitizing agent to the community.

In 2021, Procurement Leaders – a community that provides strategy development and peer-to-peer benchmarking for Chief Procurement Officers – decided to replace their World Procurement Awards with a one-off celebration: Extraordinary Stories. These stories, from organizations across the globe recognize how procurement has stepped up in times of strain to support business performance, protect local communities and save lives during the pandemic.


Luís Portela, Procurement Director at Hovione, was invited to tell Hovione’s extraordinary story through this period. In a short video he explains how we produced and supplied for free, sanitizing agents at a time where this was scarcely available and speculation drove prohibitive prices.


We adapted sectors of our industrial facilities to produce sanitizing agent and made it available for free to our Team Members at work and at home, as well as to healthcare and social supporting institutions. This was only possible with a team effort while we continued to produce medicines that save lives without disruptions.


Watch the video at Procurement

Learn more about our efforts in the article "Stepping up to the hand sanitizer shortage" by C&EN.





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Continuous Tableting (CT) is defined as continuous manufacturing of oral dose drugs, specifically tablets. As per ICH's Q13 definition1, a continuous manufacturing process in the pharmaceutical industry comprises at least two unit operations integrated from a mechanical and software perspective. There is a wide combination of possible CT process configurations that are dependent on the needs of the intended product formulation and each of the individual unit operations that constitute the process train can be continuous, semi-continuous, or batch processes. The typical manufacturing processes for tablet formulation are direct compression (DC), dry granulation (DG) and wet granulation (WG)2 - details on these manufacturing processes are beyond the scope of this article, so the interested reader is directed to relevant literature. The actual implementation of CT technology in a facility can broadly vary depending on the level of desired integration and automation. Process trains can be designed to be flexible and converted between multiple configurations (e.g. continuous DC, DG and WG), controlled by the end user from one single software and within a single clean room. The other possibility would be for subsections of the CT process to be divided into multiple clean rooms where inprocess materials are transferred between suites via a bin-to-bin approach (e.g. a granulation suite to prepare granules from raw materials followed by continuous DC (CDC) to blend the granules and produce tablets). The level of automation and instrumentation designed into the CT process (typically involving Process Analytical Technologies, PAT) can open the possibility to implement sophisticated control strategies. Key components of a control strategy that need to be considered for CT are material tracking and genealogy, knowledge of the residence time distribution (RTD), and in-process controls (spectroscopic and/or soft sensors based on process parameters). Holistically, these control strategy elements enable the implementation of a material diversion strategy to automatically divert out of specification material from the process. In their most advanced form, control strategies may also enable real time release testing (RTRt) of the final tablet drug product and reduce the off-line analytical burden and the number of operators needed to manage the process.   Read the full article at  


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