Hovione is presenting at the CRS 2026 Annual Meeting, taking place in Lisbon, Portugal. The conference will explore groundbreaking advancements and transformative ideas in controlled release science and technology. Join the Hovione team for an inspiring week of insightful presentations, engaging discussions, and unparalleled networking opportunities with leading experts and innovators from around the world.
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Don’t miss the chance to speak with our experts and learn how we are advancing a differentiated offering in Biologics and Complex Injectables, from early development through to cGMP supply.
HOVIONE TECHNICAL FORUM
Rational Formulation Strategies for High Concentration Subcutaneous Biologics: From Innovative Excipients to Spray Dried Drug Product Suspensions
July 7, 9:00–10:00 AM (WEST)
Joana Cristóvão, Ph.D. | R&D, Analytical Senior Manager
Inês Matos, Ph.D.| R&D, Inhalation & Advanced Drug Delivery Manager
Innovative formulation and manufacturing strategies are accelerating the shift from intravenous (IV) to patient-friendly subcutaneous (SC) delivery of biologics. This transition is driven by strong patient preference, reduced healthcare burden, and the opportunity for at-home administration. But challenges remain, especially for high-dose biologics.
At the Hovione Technical Forum, in a single session, two complementary presentations will showcase how advanced formulation science and particle engineering are expanding the possibilities for efficient, scalable, and patient-centric biologic therapies:
- Learn more about novel excipient design strategies to reduce viscosity and enhance stability in high-concentration liquid formulations
- Get insights on spray drying as an enabling technology for biologics, unlocking new solid-state and ultra-concentrated formats
ORAL PRESENTATION
Addressing Nasal Delivery Challenges: Integrated Formulation and Device Strategies for Predictive Performance
July 8, 2:53 PM - 3:16 PM WEST
Patrícia Henriques, Ph.D. | Scientist, Inhalation and Advanced Drug Delivery
Nasal powder delivery is emerging as a versatile platform for both local and systemic administration, as well as nose-to-brain applications. This presentation will highlight an integrated, evidence-driven development approach combining formulation design, particle engineering, device selection, and translational in vitro tools to enable targeted deposition and improved bioavailability.
Starting from a deep understanding of the API, the presentation will address excipient selection, process development, and particle engineering approaches, together with fit-for-purpose analytical and device considerations. Case studies will illustrate how these elements work together to address key development challenges, including dose constraints and the delivery of complex or poorly soluble therapeutics, supporting robust and performance-driven nasal powder products.
POSTERS & Poster Presenter
- (113) Looking Beyond Aerodynamics: Evaluation of Fluticasone Furoate via Dissolution and Permeation using Lung ALIs
Beatriz Gamelas, M.Sc.| Ph.D. Candidate, Analytical DevelopmentLearn more about the importance of developing robust dissolution and permeation methods to study drug bioavailability and ensure consistent performance of orally inhaled drug products (OIDPs) for early formulation screening
- (132) Why Model Structure Matters: Translatability Across Inhalation PBPK Frameworks
Filipa Ferreira, Pharm.D., Ph.D. | Senior Scientist II, Translational Lead | InnovationLearn how inhalation PBPK model structure influences the prediction of pulmonary and systemic drug exposure, and why regional lung deposition and permeability are key drivers of pharmacokinetic outcomes.
- (502) Innovative Synthetic Sugars for Stable, Low-viscosity High-Concentration Biologic Formulations
Joana Cristóvão, Ph.D. | R&D, Analytical Senior ManagerHigh-concentration biologics don't have to be viscous. With this poster, learn how Hovione Synthetic Sugars are solving one of the biggest challenges in subcutaneous biologic delivery.
- (655) Optimizing CRISPR/Cas9 Polymeric Nanoparticle Formulations: From In Silico Insights to Microfluidics and Stability Strategies
Andreia Sofia Pereira | Student, Inhalation and Advanced Drug DeliveryNeurological disorders are the leading global cause of disability, driving an urgent demand for brain regeneration therapies. Learn how Hovione is contributing to the @REGENERAR project, optimizing both the formulation and manufacturing process of engineered nanoparticles (NPs) to reprogram non-neuronal cells for neuronal regeneration.
Ask us how we’re advancing more patient centric therapies through proprietary excipients, such as synthetic sugars, and spray dried approaches that unlock alternative dosage forms.