Press Room

2023 AIChE Annual meeting

Start
Sunday, November 05, 2023 - 09:00
End
Friday, November 10, 2023 - 17:00
Location: Orlando, United States
AIChE 2023 Annual Meeting | Hovione

Meet Hovione team at the 2023 AIChE Annual Meeting and find their exciting presentations and Hovione’s latest research and innovations. The AIChE Annual Meeting is an educational forum covering a wide range of topics relevant to cutting-edge research, new technologies, and emerging growth areas in chemical engineering. We look forward to meeting academic and industry experts and exchanging knowledge.

 



Date: November 5, 2023

Oral Presentation 547b

Title: PAT Development Strategy in the Feed Frame As an Enabler for Faster Continuous Manufacturing Implementation

Presenting Author: Pedro Durão (Senior Scientist II, Modelling & PAT)

3:51 PM - 4:12 PM

Celebration 7 (Convention Level)

Oral Presentation 653f

Title: Modeling Continuous Film Coating Process in Consigma Coater: What Changes?

Presenting Author: Pedro Monteiro (Scientist, Formulation Development)

5:15 PM - 5:36 PM

Celebration 8 (Convention Level)

Oral Presentation 653g

Title: Model-Based Application for a Safe Scale-up and Equipment Selection on a Pressure Generating Pharmaceutical Process

Presenting Author: Frederico Montes (Scientist, Corporate Technical Services)

5:36 PM - 5:57 PM

Celebration 8 (Convention Level)



 

Date: November 6, 2023

Session 113 - Particle Characterization

Chair: Sarang Oka, Continuous Manufacturing Development Engineer

12:30 PM - 3:00 PM

Bayhill 19 (Lobby Level)

Poster Presentation 198d

Title: Development and Application of Residence Time Distribution (RTD) Models for a Continuous Direct Compression Process

Presenting Author: José Granjo (Modelling & PAT Scientist)

3:30 PM - 5:00 PM

Regency Ballroom R/S (Convention Level) 

Poster Presentation 198v

Title: Cryo Jet Milling for Micronization Enhancement of Inhalation Particles

Presenting Author: Inês Gomes (IST), with João Pires, Filipe Vultos, Ricardo Velez (Scientists, Hovione) and Ana Azevedo (IST)

3:30 PM - 5:00 PM

Regency Ballroom R/S (Convention Level)

Poster Presentation 643g

Title: A Template for Investigating NIR Spectroscopy-Based Deviations

Presenting Author: Ankita Naik (Modelling & PAT Scientist, CM Process Development)

5:36 PM - 5:57 PM

Celebration 8 (Convention Level)



 

Date: November 7, 2023

Oral Presentation 500g

Title: Recent Advances in ASD Formulations: Combining Dispersome® Technology with a High-Throughput Screening Setup

Presenting Author: Inês Ramos (Senior Scientist, Formulation Development)

1:08 PM - 1:26 PM

Manatee Spring II (Lobby Level)

Oral Presentation 500h

Title: Amorphous Solid Dispersions By Spray Drying: From Early Formulation to Commercial Lifecycle Management

Presenting Author: José Luís Santos, Director, Technology Intensification

1:26 PM - 1:44 PM

Manatee Spring II (Lobby Level)

Oral Presentation 583a 

Title: Impact of Rheology and Process Variables on the Development and Scale-up of a Drum Filling Process for Dry Powder Inhalers

Presenting Author: Rui Churro (Senior Scientist, Process Development)

3:30 PM - 3:51 PM

Celebration 8 (Convention Level)

Oral Presentation 583d

Title: Droplet to Particle model prediction by coupling solution rheological characterization, CFD and Phase doppler analysis

Presenting Author: Márcia Tavares (Scientist, Process Development)

4:33 PM - 4:54 PM

Celebration 8 (Convention Level)



 

Date: November 8, 2023

Oral Presentation 74c

Title: Bridging Crystallization and Mechanical Properties to Particle Size Reduction Efficiency in Jet Milling Industrial Pharmaceutical Processes

Presenting Author: Gonçalo Marcelo (Scientist, Particle Engineering)

9:00 AM - 9:20 AM

Bayhill 19 (Lobby Level) 

Poster Presentation 303r

Title: Integrating Three-Fluid Nozzle Technology as a QbD Tool for Enhancing Advanced Respiratory Drug Delivery Formulations: A Statistical Modeling Approach 

Presenting Author: Rui Churro (Senior Scientist, Process Development)

3:30 PM - 5:00 PM

Regency Ballroom R/S (Convention Level)

Poster Presentation 84at

Title: Asset Intensification: Application of Modelling Tools and Methodologies from a CDMO Perspective

Presenting Author: Filipe Ataide (Senior Scientist, Technology Intensification)

3:30 PM - 5:00 PM

Regency Ballroom R/S (Convention Level)

 

 

Date: November 9, 2023

Oral Presentation 355e

Title: Controlled Crystallization through Microfluidization As an Alternative Particle Engineering Technology for Inhalation Products

Presenting Author: Gonçalo Marcelo (Scientist, Particle Engineering)

9:24 AM - 9:45 AM

Celebration 8 (Convention Level)

Oral Presentation 649e

Title: Use of Statistical Process Control to Drive Process Improvements in Continuous Manufacturing

Presenting Author: Ankita Naik (Modelling & PAT Scientist, CM Process Development)

4:58 PM - 5:20 PM

Celebration 8 (Convention Level)

 

 

 

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The CDMO’s New Jersey manufacturing site expansion will eventually cover more than 200,000 square feet. Portugal-based contract development and manufacturing organisation (CDMO) Hovione has completed an initial $100 million investment round in its East Windsor, New Jersey site. Once completed it will increase the facility’s footprint to more than 200,000 square feet and more than double its capacity for spray drying. Hovione CEO Jean-Luc Herbeaux said: “Since launching our New Jersey operations in 2002, Hovione has been one of the longest established European CDMOs in the United States. “This investment reinforces Hovione’s leadership in spray drying – a core technology platform where we have built extensive know-how and capabilities. By continuing to advance our platforms and expand capacity in the US, we are strengthening the foundation that enables our partners to bring complex medicines to patients more efficiently.” Spray drying is an increasingly important particle engineering technology for improving drug bioavailability through the amorphous solid dispersion (ASD) that can address bioavailability or crystallisation challenges. The initial phase of Hovione’s expansion will include a 31,000-square-foot building to house two size-3 spray dryers (PSD-3) designed for ASD production. Construction at the New Jersey site is already underway and the company plans to start GMP operations in the second quarter of 2026. The initiative is part of Hovione’s long-term strategy to grow its US operations and enhance its integrated drug substance, drug product intermediate and drug product capabilities. Herbeaux said: “This investment addresses growing customer demand for US-based capacity and integrated solutions that shorten development timelines and reduce tech transfer complexity. By consolidating development, scale-up, and commercial manufacturing within a single quality and governance framework, we provide customers with seamless execution from drug substance to drug product.” The company’s New Jersey expansion fits into its wider international growth plan that also includes capacity investments in Ireland and Portugal as it seeks to create a network of autonomous sites spanning the development and commercialisation of APIs, drug product intermediates and drug products.   Read the full article at EuropeanPharmaceuticalReview.com  

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The latest from CDMOs, CMOs, and suppliers featuring Thermo Fisher Scientific, Lonza, SK pharmteco/Lotte Biologics, Hovione, Sai Life Sciences, BioCina, Alcami, Piramal Pharma/IntoCell and Roquette. Formulation Development/Drug Product Manufacturing: Hovione Completes Initial $100-M Investment Cycle in US Operations Hovione, a CDMO of drug substances and drug products, has completed an initial $100-million investment cycle at its site in East Windsor, New Jersey, as part of a strategy to increase its US operations and enhance its integrated drug-substance, drug-product intermediate, and drug-product capabilities. Upon completion, the site will cover more than 200,000 square feet.   The initial expansion phase includes a 31,000-square-foot building that will house two size-3 spray dryers (PSD-3) designed for production of amorphous solid dispersions (ASDs). This investment more than doubles Hovione’s spray-drying capacity in the US by expanding capabilities for ASD development and commercial manufacturing. Construction is underway at the New Jersey site, with GMP operations planned to start in the second quarter of 2026.  As part of this expansion, Hovione has also acquired additional adjacent land to enable future growth at the East Windsor site. The 125,000-square-foot greenfield will support large-scale production, including continuous and batch tableting capacity, and introduce the latest pharmaceutical technologies and digital innovation with enhanced quality control and R&D capabilities.    Read the full article at DCATvci.org  

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