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Article / Jan 01, 2007

The survival of the fittest. Where have great European brands gone?

Pharmaceutical Technology Europe, January 2007

At the turn of the century, chemical giants spent about $3 billion in two years buying up pharmaceutical fine chemical specialists. This was part of a wider restructuring that added up to $14 billion of M&A activity between 1998–2000 in fine chemicals. Certainly in the last decade there have been three major waves of restructuring:

  • Pharma giants increasing their market share through mergers while shedding chemical operations.
  • The emergence of “new”chemical companies such as Avecia, Ciba, Clariant, Degussa, Rhodia and Solutia.
  • Traditional companies radically restructuring or simply disappearing.

Leading consultants and financial analysts succeeded in convincing these companies that pharmaceutical fine chemicals would be a high growth, high margin, noncyclical sector with synergies with their existing businesses. Quel désastre.

 

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Integrated approach simplifies development, reduces risk, and supports scalable manufacturing. Hovione and Industrial Design Consultancy Ltd.’s (IDC) lead single-use nasal dry powder device is now available for commercial partnerships. Hovione and IDC have completed the device design and established initial device manufacturing and supply capability, enabling pharmaceutical partners to leverage existing capsule filling infrastructure. This approach simplifies development, reduces cost and risk, and helps shorten timelines to the clinic and commercialization. “This milestone marks an important step in the evolution of our collaboration with IDC — from device innovation to a fully integrated intranasal drug delivery platform,” said Márcio Temtem, Ph.D., Vice President, Strategic Business Management, Hovione. “As the industry looks for faster, more reliable ways to bring complex therapies to patients, integration becomes critical. By bringing together nasal particle engineering science, formulation manufacturing and filling, and device technologies into a single offering, we enable a more seamless and predictable development journey, accelerating the path to market for intranasal therapies.” The nasal delivery device enables broad and targeted nasal deposition flexibility while delivering maximum usability and reliability. With a patented design and manufacturing process established, the platform is available for partnering with pharmaceutical companies on an exclusive basis as part of Hovione’s integrated offering for inhalation and nasal drug development and manufacturing. Additionally, IDC’s Managing Director, Stephen Knowles Ph.D., said the companies are now “well-advanced” with the development of a multi-use device to support an even wider range of therapies and patient needs. Read the full article at ContractPharma.com    

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