Press Room

News / Oct 08, 2019

Celebrating our 60th Anniversary in Cork

10 years in Cork, 60 years in the world.

On September 5th 2019, Hovione celebrated its 60th anniversary at the Cork site in Ireland.

The event joined together team members, clients and stakeholders that make Hovione a great Company.

Guy Villax Simon Coveney Manufacturing Plant Ringaskiddy Cork, Ireland | Hovione
Guy Villax and Simon Coveney, Tánaiste and Minister for Foreign Affairs and Trade of Ireland

 

“I’m delighted to see the Cork site playing such an important part in the success of this impressive company,” said Simon Coveney TD, Tánaiste and Minister for Foreign Affairs and Trade speaking at the celebration event for Hovione’s 60th anniversary.

“Hovione has seen steady growth over the last few years and I’m confident that the coming years will be equally successful for the Cork team.”

 

60th Anniversary in Cork | Hovione
Paul Downing and Simon Coveney, Tánaiste and Minister for Foreign Affairs and Trade of Ireland

 

Celebrating 60th Anniversary in Cork | Hovione
Photo Group
60th Anniversary in Cork | Hovione
Ambassador of Portugal in Ireland, Miguel de Almeida e Sousa, Guy Villax and Paul Downing

 

“Our Cork site plays a significant and strategic role within the Hovione network,” said Hovione CEO, Guy Villax. “With two Active Pharmaceutical Ingredient facilities alongside a Drug Product Intermediate facility that houses the largest commercial pharmaceutical spray dryer in operation, the Cork site boasts both extensive manufacturing capacity and people capability.”

 

Guy Villax Paul Downing at Manufacturing Plant in Cork Ireland | Hovione
Guy Villax, Paul Downing and a Cork tree from Portugal in Cork

 

 

 

 

Also in the Press Room

See All

Continuous Tableting (CT) is defined as continuous manufacturing of oral dose drugs, specifically tablets. As per ICH's Q13 definition1, a continuous manufacturing process in the pharmaceutical industry comprises at least two unit operations integrated from a mechanical and software perspective. There is a wide combination of possible CT process configurations that are dependent on the needs of the intended product formulation and each of the individual unit operations that constitute the process train can be continuous, semi-continuous, or batch processes. The typical manufacturing processes for tablet formulation are direct compression (DC), dry granulation (DG) and wet granulation (WG)2 - details on these manufacturing processes are beyond the scope of this article, so the interested reader is directed to relevant literature. The actual implementation of CT technology in a facility can broadly vary depending on the level of desired integration and automation. Process trains can be designed to be flexible and converted between multiple configurations (e.g. continuous DC, DG and WG), controlled by the end user from one single software and within a single clean room. The other possibility would be for subsections of the CT process to be divided into multiple clean rooms where inprocess materials are transferred between suites via a bin-to-bin approach (e.g. a granulation suite to prepare granules from raw materials followed by continuous DC (CDC) to blend the granules and produce tablets). The level of automation and instrumentation designed into the CT process (typically involving Process Analytical Technologies, PAT) can open the possibility to implement sophisticated control strategies. Key components of a control strategy that need to be considered for CT are material tracking and genealogy, knowledge of the residence time distribution (RTD), and in-process controls (spectroscopic and/or soft sensors based on process parameters). Holistically, these control strategy elements enable the implementation of a material diversion strategy to automatically divert out of specification material from the process. In their most advanced form, control strategies may also enable real time release testing (RTRt) of the final tablet drug product and reduce the off-line analytical burden and the number of operators needed to manage the process.   Read the full article at gmp-journal.com  

Article

Continuous Tableting and the Road to Global Adoption

Mar 04, 2024