Knowledge Center

Patent / Jan 01, 1972

Polymetaphosphate complexes of .alpha.-6-deoxy-5-hydroxy tetracyclines

Authors:
  • Ivan Villax
Source:
DE 2152476

The title Na phosphate complexes, useful as antibiotics and more sol. in water than the corresponding acid complexes, were prepd. by reaction of the tetracycline with Na hexametaphosphate or HPO3 then NaOH in an inert org. solvent, e.g., DMF, EtOH, MeOH, or CHCl3.

Also in the Knowledge Center

Related Content

The Hovione Experience - Lisbon

Welcome to Lisbon! Part of The Hovione Experience is ensuring your trip is unforgettable. Explore our suggestions for iconic attractions, exquisite cuisine, and get ready to feel the magic of this vibrant city.

Page
Read more

Jet milling

Jet milling is widely used in the pharmaceutical industry and remains the leading technology for particle size reduction and is most commonly used for having consistent and uniform particles during formulation.

Page
Read more

Continuous Tableting for Drug Product

Hovione´s pragmatic approach to bridging science with manufacturing is now being leveraged for continuous tableting and it is the key to ultimately providing high quality medicines and the success of your drug product.

Page
Read more