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Patent / Jan 01, 1976

16.beta.-Methyl-17-hydroxypregna-1,4,9(11)-triene-3,20-dione

Authors:

Source:

GB 1397267

The title compd. I was prepd. from pregnanetrione II. Thus, ketalization of II using HOCH2CH2OH followed by redn. using KBH4 and then dehydration gave pregnene III. The Grignard reaction of III and MeMgBr followed by acid hydrolysis and bromination-dehydrobromination gave I.

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Knowledge Center

16.beta.-Methyl-17-hydroxypregna-1,4,9(11)-triene-3,20-dione

Also in the Knowledge Center

Hovione and Invion sign development agreement for first inhaled non-steroidal anti-inflammatory for asthma

Improving the Aerodynamic Performance of Fluticasone Propionate Powders by Tuning Particle Size through Wet Polishing

Optimization of a Roller Compaction Process for a Spray Dryer Formulation Using Powder Rheology

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