Knowledge Center
Patent / Jan 01, 1976
16.beta.-Methyl-17-hydroxypregna-1,4,9(11)-triene-3,20-dione
Source:
GB 1397267
The title compd. I was prepd. from pregnanetrione II. Thus, ketalization of II using HOCH2CH2OH followed by redn. using KBH4 and then dehydration gave pregnene III. The Grignard reaction of III and MeMgBr followed by acid hydrolysis and bromination-dehydrobromination gave I.
Also in the Knowledge Center
/ May 29, 2025
Mitigating Shear Stress in Spray Drying for RNA‑Loaded Lipid Nanoparticles through Process and Formulation Optimization
Read more
Scientific Article
/ Jun 01, 2025
Improving inhalation delivery of biologics with extra-large particles produced by spray freeze drying
Read more
Scientific Article
/ Jun 20, 2025
Material-sparing method development for liquid-to-solid ratio determination for wet granulation process development
Read more
Scientific Article