For decades, organic solvents have been the workhorse of the chemical industry, serving as indispensable media for numerous reactions. Traditionally, chemists have favoured organic solvents for their ability to facilitate a wide range of reactions. Their use has also been a cornerstone of pharmaceutical manufacturing.

However, this choice carries environmental consequences that cannot be ignored. As a major organic solvent consumer, the pharmaceutical industry significantly contributes to the generation of chemical waste, often containing hazardous by-products that cause environmental pollution and disrupt ecosystems. Organic solvents are responsible for more than 80% of pharma mass utilization.

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