Press Room

Press Release / Sep 26, 2025

Hovione honored with the Leonardo da Vinci Prize 2025

Presented by the Hénokiens Association and the Château du Clos Lucé

Leonardo da Vinci Prize | Hovione

Lisbon, Portugal, 25 September 2025 – Hovione, a Portuguese-founded multinational and family-owned business specialized in the development and manufacturing of pharmaceutical products, has received the Leonardo da Vinci Prize 2025, awarded by the Hénokiens Association and the Château du Clos Lucé. In its 14th edition, the prize was presented in Lisbon to Ms. Diane Villax, founder and member of the Board of Directors of Hovione, by former Portuguese Deputy Prime Minister Paulo Portas, before an audience of global business leaders and public figures.

“This award recognizes Hovione’s commitment to science, innovation and service to patients worldwide. It reflects the values that have guided us from the start – honesty, integrity, scientific rigor and teamwork – with a long-term vision that puts people and progress at the center. Above all, it is a tribute to the people of Hovione, whose passion and dedication ensure we remain, in every sense, In it for life,” said Diane Villax, Founder and member of the Board of Directors of Hovione.

“This recognition strengthens our resolve to build for the future, drawing on our heritage, culture, and the passion of our employees as we expand our global reach to partners and patients. We remain dedicated to advancing innovation, deepening partnerships with the pharmaceutical industry, and ultimately helping deliver better medicines to improve lives,” said Dr. Jean-Luc Herbeaux, CEO of Hovione.

Founded in 1959, Hovione remains a family-owned company, employing 2,400 people across five manufacturing facilities (Loures and Seixal - Portugal; New Jersey - US; Cork - Ireland; and Macau), two R&D centers, and eight regional offices worldwide. With a strong scientific foundation, the company supports the pharmaceutical industry in addressing its most complex challenges and has contributed to 29 new drugs approved by the US FDA in the last decade, representing in some years as much as 10% of the total, improving the lives of an estimated 80 million patients every year.

Hovione has played a decisive role in some of the world’s greatest public health breakthroughs - from manufacturing ivermectin, the Nobel Prize-winning treatment for river blindness, to producing three of the four hepatitis C drugs that have cured over 4 million patients, and enabling the world’s first COVID-19 approved treatment, Veklury®, which reached 6.5 million patients. Beyond science, the company has shown a strong commitment to society, from donating nearly 1 million bottles of sanitizing gel during the pandemic, to investing in education through supporting Nova University school of Sciences and Technologies, the significant financial contribution to NOVA School of Business and Economics, among other, and recently becoming the new official sponsor of the Portuguese National Rugby Team, including support for youth talent development.

 

About Hovione
Hovione is an international company with over 60 years of experience in pharmaceutical development and manufacturing operations. As a Contract Development and Manufacturing Organization (CDMO) it has a fully integrated offering of services for drug substances, drug product intermediates and drug products. The company has four FDA inspected sites in the USA, Portugal, Ireland and China and development laboratories in Lisbon, Portugal and New Jersey, USA. Hovione provides pharmaceutical customers services for the development and compliant manufacture of innovative drugs, including highly potent compounds, and customized product solutions across the entire drug life cycle. In the inhalation area, Hovione offers a complete range of services, from API, formulation development and manufacturing, capsule filling and devices. Hovione's culture is based on innovation, quality and dependability. Hovione is a member of Rx-360, EFCG and participates actively in industry quality improvement initiatives to lead new global industry standards.

About Henokiens Association
The International Henokiens Association, created in France in 1981, brings together bicentennial family businesses from around the world. Descendants of the founders are still the owners or majority stakeholders of the 57 member companies, based in 10 countries. Through its members and the values they embody, the association aims to promote the concept of the family business as an alternative to multinationals. www.henokiens.com

About Château du Clos Lucé
Château du Clos Lucé - Parc Leonardo da Vinci, located in Amboise, is the residence where Leonardo da Vinci settled in 1516 at the invitation of King Francis I. Appointed “First Painter, Engineer and Architect to the King”, he worked tirelessly on numerous projects before passing away 500 years ago. The Saint Bris family has owned the property since 1855, and opened this cultural landmark to the public almost one hundred years later, in 1954. The family’s mission is to pass on the universal heritage, memory and knowledge of Leonardo da Vinci’s work to as many people as possible. In 2019, the Château du Clos Lucé welcomed 520,000 visitors, 25% of whom were from abroad. It is the 3rd most visited monument in the Loire Valley. Thanks to digital technologies, Clos Lucé is continuing its digital transformation and in June 2021 inaugurated the Leonardo da Vinci Painter and Architect Galleries, a new 500 square metre cultural facility. Visitors are immersed in the creative process and the entire painted work of the Renaissance genius in an immersive audiovisual show. www.vinci-closluce.com/en

 

 

Also in the Press Room

See All

The investment includes both continuous and batch tableting capabilities, as well as connect spray drying with tablet production at its East Windsor campus. Hovione, a Portugal-based contract development and manufacturing organization (CDMO), plans to install a continuous tableting line at its East Windsor, New Jersey campus, adding drug product manufacturing capacity and an integrated pathway from amorphous solid dispersion production through commercial tablet manufacturing. The $35 million investment will bring the first ConsiGma CDC Flex system to Hovione’s recently opened 89 Twin Rivers facility. The line is expected to be commissioned in late 2027 and will support both continuous and batch operation at throughputs ranging from 1 to 200 kilograms per hour, according to the announcement. The system will allow customers to use the same equipment for development, clinical, and commercial production, with formulation development possible using as little as 1.5 kilograms of material. Hovione said the line will also be equipped for containment to 1 microgram per cubic meter to support the handling of highly potent compounds. The new capability will also connect Hovione’s spray-drying operations with tablet manufacturing at the East Windsor campus. The company recently opened a 31,000-square-foot facility at the campus with two commercial-scale spray dryers for manufacturing amorphous solid dispersions (ASDs), completing a $100 million investment in its New Jersey operations. Hovione said the integrated setup will allow customers to move from formulation and particle engineering through tablet production under one quality system, reducing technology transfer requirements and eliminating traditional scale-up between development and commercial production. The ConsiGma CDC Flex platform was jointly developed with GEA as part of a collaboration that began in 2022, the company said. The system incorporates automated process controls and process analytical technology for real-time monitoring during production. Hovione already operates continuous tableting technology at its Loures, Portugal site. In August, the company completed a more than €40 million expansion of its tablet development and manufacturing center there, adding a second commercial-scale tableting line and increasing the center's manufacturing area by 25%. The East Windsor installation will extend Hovione’s continuous tableting capabilities to the U.S. and expand its integrated drug development and manufacturing services for oral solid dosage products. Read the full article at Pharma Manufacturing 

Press Clipping
Pharma Manufacturing, 6 October 2026

Hovione to add $35M continuous tableting line at New Jersey site

Oct 06, 2026

Hovione, a globally integrated pharmaceutical contract development and manufacturing organisation (CDMO), will commission the world’s first ConsiGma CDC flex – a next generation continuous tableting line – at its East Windsor, New Jersey (USA) campus in late 2027. The line will be installed at 89 Twin Rivers, Hovione’s recently opened facility, expanding the company’s drug product capabilities and strengthening its integrated pharmaceutical development and manufacturing hub in the US. CDC ConsiGma flex system The project represents an investment of $35 million. Once installed it will create an integrated pathway from amorphous solid dispersion manufacturing via spray drying through commercial tablet production. The new flex will operate in continuous or batch modes across a very broad throughput range (from one to 200 kg/h). Customers will be able to develop a formulation using small quantities of material, down to 1.5 kg, and then run from very small clinical batches to large commercial batches using the same equipment. This is enabled by specialised design within the flex to effectively switch between continuous blenders of various sizes. Additionally, the line will be installed for containment to 1 µg/m³, supporting highly potent compounds. Continuous tableting is reshaping manufacturing of oral solid dosage medicines and is well suited to programmes in which speed, supply resilience and efficient use of high-value active pharmaceutical ingredients (APIs) are priorities. Inline process analytical technology (PAT) and automated controls also provide real-time quality monitoring. In parallel, the 2022 adoption of ICH Q13 regulatory framework, guidance specifically for continuous manufacturing of drug substances and drug products, provides harmonisation across the US, Europe and Japan. As of 2024, 17 products manufactured under the international guidance have been approved by the US Food and Drug Administration (FDA) alone.  Developed jointly with GEA, the ConsiGma CDC flex platform also incorporates SimpleCT, a suite of automation and control tools with smart interfaces that supports a single process from development to commercial supply. Designed for versatility and ease of use, these innovative developments simplify operation, improve efficiency and containment, and enhance operator safety. Read the full article at Pharma Press UK 

Press Clipping
Pharma Press Global, 6 October 2026

Hovione to commission world’s first ConsiGma CDC flex, bringing next-generation continuous tableting to the US

Oct 06, 2026

Key Takeaways Commissioning a US-based ConsiGma CDC Flex line enables end-to-end spray drying-to-tablet manufacture within a single site and quality system, reducing comparability and technology-transfer burdens. Elimination of conventional scale-up is enabled by using the same equipment from early development through commercial supply, minimizing engineering runs and conserving scarce API. Operational flexibility spans batch or continuous modes and 1–200 kg/h throughput, with scale adjustment achieved by switching continuous blenders rather than replatforming processes. High-containment design to 1 µg/m³ expands suitability for highly potent oral solid-dose programs while maintaining integrated development-to-commercial workflows. Regulatory momentum for continuous manufacturing is supported by ICH Q13 harmonization, increasing FDA approvals, and platforms leveraging inline PAT and automated control suites for real-time quality assurance. Hovione announced on Oct. 5, 2026, that it will commission the ConsiGma CDC Flex, a next-generation continuous direct compression tableting platform jointly developed with GEA. The investment is designed to link amorphous solid dispersion manufacturing via spray drying with commercial tablet production at a single US site operating under one quality system. The line will run in either continuous or batch mode at throughputs from 1 to 200 kg/h. Formulation development can begin with as little as 1.5 kg of material, and the same equipment can then support everything from very small clinical batches to large commercial runs, enabled by a design that allows the system to switch between continuous blenders of different sizes. The installation will also be contained to 1 µg/m³ to accommodate highly potent compounds. "Hovione will be the first company in the world to offer the ConsiGma® CDC Flex, bringing this next-generation technology with unprecedented flexibility, simplicity and cost-efficiency in continuous tableting," said Marco Gil and António Almeida, co-CEOs, Hovione, said in a press release. "This investment also advances our strategy of building integrated capabilities close to customers in key markets. By adding this new line at East Windsor, we are broadening access to this technology in the U.S. and giving customers a more direct and accelerated path for developing and commercializing complex oral medicines." What Does a Single Development-To-Commercial Line Change? For formulators and process engineers, the most consequential claim is the removal of traditional scale-up. Moving a process from development equipment to commercial equipment typically requires engineering runs, bridging work, and consumption of scarce API, all of which weigh heavily on early programs with limited material. "Installing the CDC Flex at 89 Twin Rivers makes continuous tableting part of an integrated US development and manufacturing workflow," said David Basile, Vice President of Technical Operations, Hovione, in the press release. "Customers can move from formulation and particle engineering to commercial tablets with one Hovione team and one quality system, eliminating traditional scale-up while gaining greater production flexibility, process control and supply continuity." Co-locating spray drying and tableting is also significant because amorphous solid dispersions remain a primary solubility-enhancement route for poorly soluble molecules, and transferring intermediates between sites or vendors adds technology transfer and comparability burdens. The new line builds on the company's earlier US expansion; Hovione recently completed a $100 million investment to bolster US capacity in particle design, amorphous solid dispersions via spray drying, and batch and continuous tableting. How Is the Regulatory Environment Shaping Continuous Tableting Adoption? The company points to the 2022 adoption of ICH Q13, which provides harmonized guidance for continuous manufacturing of drug substances and drug products across the US, Europe, and Japan. Hovione reports that, as of 2024, FDA alone had approved 17 products manufactured under the guidance. Speaking on ICH Q13, FDA's Kelley Burridge, PhD, "Perceived barriers to continuous manufacturing have been falling one by one," and noted an FDA publication showing faster approval times for products with continuous manufacturing elements than for comparable batch products. The platform incorporates inline process analytical technology and automated controls for real-time quality monitoring, along with SimpleCT, an automation and control suite intended to support a single process from development through commercial supply. For sponsors weighing supply resilience and regional sourcing, the East Windsor installation extends a capability that Hovione says only it currently offers as a contract development and manufacturing organization.   Read the full article at PharmTech.com  

Press Clipping
PharmTech, 5 October 2026

Can Continuous Tableting End Scale-Up for Complex Oral Drugs?

Oct 05, 2026

Also in Events

See All