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Press Clipping / Nov 13, 2017

Growth strategies for pharmaceutical chemical makers on display at CPhI

C&EN, November 13, 2017

Frankfurt expo showcases a transformation in contract R&D and manufacturing of drug ingredients.

The pharmaceutical chemical sector is experiencing a prolonged period of profitability and a wave of transformation as companies invest profits in new ventures and new capacity. A picture of how the sector is evolving came into focus last month when CPhI Worldwide, the annual pharmaceutical ingredients exhibition, came to Frankfurt.

The event­—the largest of its kind in the world, attended by more than 40,000 people—followed a year and a half of robust merger and acquisition . . .

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Integrated approach simplifies development, reduces risk, and supports scalable manufacturing. Hovione and Industrial Design Consultancy Ltd.’s (IDC) lead single-use nasal dry powder device is now available for commercial partnerships. Hovione and IDC have completed the device design and established initial device manufacturing and supply capability, enabling pharmaceutical partners to leverage existing capsule filling infrastructure. This approach simplifies development, reduces cost and risk, and helps shorten timelines to the clinic and commercialization. “This milestone marks an important step in the evolution of our collaboration with IDC — from device innovation to a fully integrated intranasal drug delivery platform,” said Márcio Temtem, Ph.D., Vice President, Strategic Business Management, Hovione. “As the industry looks for faster, more reliable ways to bring complex therapies to patients, integration becomes critical. By bringing together nasal particle engineering science, formulation manufacturing and filling, and device technologies into a single offering, we enable a more seamless and predictable development journey, accelerating the path to market for intranasal therapies.” The nasal delivery device enables broad and targeted nasal deposition flexibility while delivering maximum usability and reliability. With a patented design and manufacturing process established, the platform is available for partnering with pharmaceutical companies on an exclusive basis as part of Hovione’s integrated offering for inhalation and nasal drug development and manufacturing. Additionally, IDC’s Managing Director, Stephen Knowles Ph.D., said the companies are now “well-advanced” with the development of a multi-use device to support an even wider range of therapies and patient needs. Read the full article at ContractPharma.com    

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