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News / Oct 23, 2018

Hovione New Jersey hosts 2018 PPAR Conference

The Pharmaceutical Process Analytics Roundtable (PPAR) Annual Event at Hovione New Jersey

New Jersey hosts 2018 PPAR Conference | Hovione

During October 15th to 17th, Hovione New Jersey hosted the Pharmaceutical Process Analytics Roundtable (PPAR) annual event. PPAR is a meeting/gathering of PAT practioneers in the Pharma industry that happens once a year where several PAT related topics are discussed (e.g.: regulatory aspects, technology novelties, people & organization, etc.).

Continuous Manufacturing have become a major topic as it makes intense use of PAT for process control and release of product.

Participants for this year event came from Pfizer, Merck, Janssen, BMS, Eli Lilly, AbbVie, Biogen, Amgen, GSK, Sanofi, Vertex, and Genentech. Nuno Matos and Savitha Panikar were the Hovione participants.

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Hovione is bringing momentum to the intranasal field after announcing that its lead single-use nasal dry powder device, developed in collaboration with Industrial Design Consultancy Ltd (IDC), is now available for commercial partnerships. The milestone marks the transition from prototype to a fully integrated intranasal drug delivery platform that spans Hovione’s end-to-end partnership capabilities–from API synthesis through advanced formulation and particle engineering to drug product manufacturing, including device supply and advanced analytical tools for nasal performance characterization. The platform’s single-use device is designed to be manufacturable at scale and to leverage existing advanced particle engineering and drug product manufacturing capabilities, a practical advantage that can shorten timelines to clinic and commercialization while reducing development risk and cost. The device’s patented mechanism supports targeted nasal deposition, including access to the upper olfactory region. This enables rapid systemic absorption and potential nose-to-brain delivery pathways that are increasingly important for CNS and emergency-use indications. Beyond the single-use format, Hovione and IDC are advancing a multi-dose variant to broaden applicability across dosing regimens and therapeutic areas. The collaboration is backed by an intellectual property portfolio and initial patent grants, positioning the platform as a turnkey option for pharma partners seeking a single integrated supplier for both drug substance and device. This development arrives as intranasal delivery gains traction for systemic, CNS and rapid-onset therapies. This is precisely the focus of the upcoming 4th Nasal Formulation & Delivery Summit, for which Hovione is a key sponsor. The annual summit unites formulation, delivery and product development leaders to tackle drug-device compatibility, translational preclinical models, and strategies for scalable, regulatory-ready intranasal programs. Hovione’s recent progress will be highly relevant to attendees looking to de-risk nose-to-brain and systemic intranasal programs. Read the full article at News-Medical.net    

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