Press Room

Webinar - One - fruitful - long shot: extended release approaches for small and large molecules

Start
Wednesday, November 25, 2020 - 16:00
End
Wednesday, November 25, 2020 - 16:00
Location: online

 

Wednesday, November 25th, 2020
4:00pm GMT   |   11:00 am EDT  |   5:00 pm CEST

 

Registrations to the webinar are subject to approval

 

 

Speakers

Cláudia Moura, PhD - Senior Scientist, R&D Drug Product Development
Teresa Marta, MSc - Associate Analytical Chemist, R&D Analytical Development

 

Drug-delivery systems administered by injection that allows controlled-release are highly desirable due to the reduced frequency of administrations that can range from weeks to months or even years, increasing patient compliance while providing the same therapeutic efficiency.

In this webinar, we will address insights into the formulation and available particle engineering technologies for controlled delivery of small molecules and biopharmaceuticals using Poly(lactic-co-glycolic) Acid (PLGA) as biodegradable polymer. We will also explore standard and advanced material characterization techniques including accelerated in vitro release (IVR) methods which have received considerable attention to expedite time required for batch release. 

This webinar will present Hovione’s approach for controlled release PLGA formulations throughout the manufacturing process and product characterization. You can hear about several manufacturing techniques available at Hovione that are followed by case-studies; the analytical characterization will also be showcased focusing on real time and accelerated IVR.

 

What can you learn from this webinar?

  • Controlled release systems - delivery routes
  • Formulation and manufacturing approaches

 

 

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Integrated approach simplifies development, reduces risk, and supports scalable manufacturing. Hovione and Industrial Design Consultancy Ltd.’s (IDC) lead single-use nasal dry powder device is now available for commercial partnerships. Hovione and IDC have completed the device design and established initial device manufacturing and supply capability, enabling pharmaceutical partners to leverage existing capsule filling infrastructure. This approach simplifies development, reduces cost and risk, and helps shorten timelines to the clinic and commercialization. “This milestone marks an important step in the evolution of our collaboration with IDC — from device innovation to a fully integrated intranasal drug delivery platform,” said Márcio Temtem, Ph.D., Vice President, Strategic Business Management, Hovione. “As the industry looks for faster, more reliable ways to bring complex therapies to patients, integration becomes critical. By bringing together nasal particle engineering science, formulation manufacturing and filling, and device technologies into a single offering, we enable a more seamless and predictable development journey, accelerating the path to market for intranasal therapies.” The nasal delivery device enables broad and targeted nasal deposition flexibility while delivering maximum usability and reliability. With a patented design and manufacturing process established, the platform is available for partnering with pharmaceutical companies on an exclusive basis as part of Hovione’s integrated offering for inhalation and nasal drug development and manufacturing. Additionally, IDC’s Managing Director, Stephen Knowles Ph.D., said the companies are now “well-advanced” with the development of a multi-use device to support an even wider range of therapies and patient needs. Read the full article at ContractPharma.com    

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