Market Data and Evolution
The current leading therapeutic class in worldwide sales is the group
of cholesterol reducing statins with overall sales of about $US15
billion in 2001. Simvastatin (Zocor®, Merck &
Co.) was the top leader in sales of worldwide prescription drugs in
2001, $US 6670 millions (26.3% increase in relation to 2000).
Simvastatin represents 44% of the sales in this therapeutic class.The market in United States valued 2,854 millions USD in 2001,
which represents 42,7% of simvastatin worldwide sales.
Simvastatin sales evolution from 1997 to 2001 and sales
distribution by country (USA, United Kingdom, Germany, France and
Japan) in 2000 and 2001, can be viewed below:
|
Simvastatin Sales - Graphs
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- Simvastatin Worldwide
Sales Evolution
(US$ millions and API tonnes)
- Simvastatin Worldwide Sales by
Country
(March 2002 (US$ millions))
|
Marketed drug products
Zocor® is Merck Sharp & Dohme’s brand name for
Simvastatin. Zocor® was first approved by the FDA in 1991.
The pharmaceutical form of Zocor® is a coated
tablet, which contains as excipients cellulose, hydroxypropyl
cellulose, hydroxypropyl methylcellulose, iron oxides, lactose,
magnesium stearate, starch, talc, titanium dioxide and butylated
hydroxyanisole as preservative1. The
pharmaceutical dosages range between 5 mg and 80 mg per tablet.
Sales distribution in the United States amongst the
available dosages can be viewed in the following graph as well as its
evolution from 2000 and 2001. The most prescribed dosage is the 20 mg.
|
Simvastatin Sales - Graphs
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- Distribution of Sales by
Dosage in the US
(Years 2000 and 2001)
|
Depending on the country there are different dosages available. As an example it is provided in the following
table the availability of dosages in the United States,
France and Germany.
|
Country |
Brand name |
Pharmaceutical dosage and
Presentation |
|
United States |
Zocor® |
5 mg
bottles of 60
tablets
bottles of
90 tablets
bottles of
100 tablets |
|
10 mg
bottles of 60
tablets
bottles of
90 tablets
bottles of
100 tablets |
|
20 mg
bottles of 60
tablets
bottles of
100 tablets |
|
40 mg
bottles of 60
tablets |
|
80 mg
bottles of 60
tablets |
|
Germany |
Zocor® |
5 mg
blister of 30
tablets
blister of
50 tablets
blister of
100 tablets |
|
10 mg
blister of 30
tablets
blister of
50 tablets
blister of
100 tablets |
|
20 mg
blister of 30
tablets
blister of
50 tablets
blister of
100 tablets |
|
40 mg
blister of 30
tablets
blister of
50 tablets
blister of
100 tablets |
|
France |
Zocor® |
5 mg
blister of 28
tablets |
|
20 mg
blister of 28
tablets
blister of
50 tablets |
|
