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Particle Design services
Hovione’s specialist capabilities in pharmaceutical fine chemicals
have been enhanced through an extensive range of advanced technologies to
address specific Particle Design problems. Building on our accumulated expertise
in micronization, freeze drying and jet milling, our new state-of-the-art
cGMP spray drying facilities give us even greater flexibility in controlling
and optimizing the particle attributes of pre-formulated APIs. Today, Hovione
can carry out a wide range of Particle Design feasibility studies, from
just a few grams to full scale commercial production, to meet your specific
particle requirements.
Particle Design technologies
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Spray drying |
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Fluidized spray drying |
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Spray congealing |
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Micronization |
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Controlled crystallization |
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Cocrystallization |
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Jet milling |
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Wet milling |
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Freeze drying |
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Ultra sound assisted crystallization |
Analytical Support:
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Malvern PSD |
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DSC |
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FTIR |
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NMR |
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SEM |
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XRPD |
Our Particle Design capabilities allow you to:
- Improve bioavailability
- Improve control over dissolution profile
- Microencapsulation
- Improve stability
- Provide an alternate method for isolating thermally labile APIs
- Manufacture directly compressible materials
- Reduce OVIs and residual solvents
- Enable life cycle management through new patents
- Provide a cost effective alternative to lyophilization |
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