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Patent / 1974

alpha.-6-Deoxytetracyclines from anhydrotetracyclines

Authors:
  • Ivan Villax
Source:
DE 2327990
Deoxycycline (I, R = OH) and 6-deoxytetracycline (I, R = H) were manufd. by fermn. of common media contg. the anhydrotetracyclines II by Streptomyces alboflavus NCIB 10,588 or S. lusitanus. I (R = OH) was isolated as hydrochloride hemihydrate hemiethanolate.