Knowledge Center

Patent / 2011

Methods and compounds for the preparation of monofluoromethylated biologically active organic compounds

Hovione Inter Limited

Authors:
  • Emilia Leitao
Source:
WO 2011151625
Processes were disclosed for the prepn. of monofluoromethylated org. biol. active compds., such as fluticasone propionate and fluticasone furoate I [R = CH2Me, 2-furanyl, resp.], in the presence of fluorodecarboxylating reagents such as XeF2 and BrF3