Chromatography

Hovione has expanded its purification technologies to include chromatography to support development from lab to commercial scale.

Chromatography

Wherever possible our process chemists attempt to avoid chromatography as a purification or isolation technique, by developing more cost efficient and scalable purification techniques involving extractions and/or crystallizations. However, given the increasing complexity of molecules and constant timeline pressures, this is not always feasible. Hovione has consequently expanded its purification technologies to include chromatography to support development from lab to commercial scale.

Also in Drug Substance Capabilities

Corticosteroids

Corticosteroids are produced in two dedicated buildings on the Loures site, which are equipped with vessels ranging from 50L up to 4000L.

Fluorinations

Hovione has a long history of carrying out reactions using hydrofluoric acid (HF) at commercial scale under a GMP environment.