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Poster / Nov 12, 2017

Spray Dried Composite Particles: Formulation and Process Parameters, Effect of two API Concentrations and Stability Assessment

Authors:
  • Maria Palha
  • Raquel Barros
  • Claudia Moura
  • Sofia Silva
  • Sara Cardoso
  • Eunice Costa
  • Marcio Temtem
Source:
AAPS 2017
In dry powders for inhalation the active pharmaceutical ingredient (API) is typically blended with excipients. However, poor drug delivery uniformity is frequently observed and the addition of a second API further increase the complexity of the formulation. In order to overcome these challenges, the engineering of carrier-free composite particles by spray drying (SD) is a suitable alternative.